CLINICAL EFFECT OF BRONCHOSCOPIC LAVAGE IN TREATMENT OF CHILDREN WITH SEVERE MYCOPLASMA PNEUMONIA

Abstract

Objective To investigate the clinical effect of bronchoscopic lavage in the treatment of children with severe mycoplasma pneumonia and its influence on pulmonary function. Methods A retrospective analysis was performed for 126 children who were diagnosed with severe mycoplasma pneumonia in Respiratory Department of our hospital from February 2018 to December 2020, and according to whether bronchoscopic lavage was performed, the children were divided into lavage group and control group, with 63 children in each group. The children in the control group were given basic pharmacotherapy alone, and those in the lavage group were treated with bronchoscopic lavage in addition to the same treatment in the control group. Related indices were collected and compared between the two groups, including duration of pyrexia, recovery time of pulmonary imaging, time to the disappearance of pulmonary rales, length of hospital stay, response rate, and pulmonary function parameters before treatment (on day 1 of hospitalization) and after treatment (on days 7-10 of hospitalization). Results There were significant differences between the lavage group and the control group in duration of pyrexia, recovery time of pulmonary imaging, time to the disappea-rance of pulmonary rales, and mean length of hospital stay (t=-8.972,-13.150,t'=-11.979,-8.650,P<0.05). The lavage group had a significantly higher response rate than the control group (z=-2.032,P<0.05). The lavage group had significant changes in VT/kg, VPEF/VE, and TPEF/TE after treatment (t=-14.161, -27.498,t'=-32.542,P<0.05). ConclusionBronchoscopic lavage has a marked clinical effect in the treatment of children with severe mycoplasma pneumonia and can significantly improve their pulmonary function.

Keywords

• bronchoscopy|bronchoalveolar lavage|pneumonia, mycoplasma|respiratory function tests|treatment outcome|child