Effects of particulate matter on allergic respiratory diseases

Jin-Zhun Wu; Dan-Dan Ge; Lin-Fu Zhou; Ling-Yun Hou; Ying Zhou; Qi-Yuan Li

Chronic Diseases and Translational Medicine (Jun 2018)

Effects of particulate matter on allergic respiratory diseases

Jin-Zhun Wu,
Dan-Dan Ge,
Lin-Fu Zhou,
Ling-Yun Hou,
Ying Zhou,
Qi-Yuan Li

Affiliations

Jin-Zhun Wu: Department of Pediatrics, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361003, China
Dan-Dan Ge: Children's Medicine Institute of Medical College, Xiamen University, Xiamen, Fujian 361102, China; Department of Translational Medicine, Medical College of Xiamen University, Xiamen, Fujian 361102, China
Lin-Fu Zhou: Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China
Ling-Yun Hou: Department of Translational Medicine, Medical College of Xiamen University, Xiamen, Fujian 361102, China
Ying Zhou: Department of Translational Medicine, Medical College of Xiamen University, Xiamen, Fujian 361102, China; Center for BioMedical Big Data Research, Medical College of Xiamen University, Xiamen, Fujian 361102, China
Qi-Yuan Li: Children's Medicine Institute of Medical College, Xiamen University, Xiamen, Fujian 361102, China; Department of Translational Medicine, Medical College of Xiamen University, Xiamen, Fujian 361102, China; Center for BioMedical Big Data Research, Medical College of Xiamen University, Xiamen, Fujian 361102, China; Corresponding author. Department of Translational Medicine, Medical College of Xiamen University, Xiamen, Fujian 361102, China.

Journal volume & issue: Vol. 4, no. 2
pp. 95 – 102

Abstract

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The health impact of airborne particulate matter (PM) has long been a concern to clinicians, biologists, and the general public. With many epidemiological studies confirming the association of PM with allergic respiratory diseases, an increasing number of follow-up empirical studies are being conducted to investigate the mechanisms underlying the toxic effects of PM on asthma and allergic rhinitis. In this review, we have briefly introduced the characteristics of PM and discussed its effects on public health. Subsequently, we have focused on recent studies to elucidate the association between PM and the allergic symptoms of human respiratory diseases. Specifically, we have discussed the mechanism of action of PM in allergic respiratory diseases according to different subtypes: coarse PM (PM2.5-10), fine PM (PM2.5), and ultrafine PM. Keywords: Particulate matter, Allergic respiratory diseases, Coarse PM, Fine PM, Ultrafine PM

Published in Chronic Diseases and Translational Medicine

ISSN: 2095-882X (Print); 2589-0514 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Medicine (General)
Website: https://onlinelibrary.wiley.com/journal/25890514

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