EXPERIENCE OF ADALIMUMAB TREATMENT IN PATIENT WITH JUVENILE ANKYLOSING SPONDYLITIS AND UVEITIS

Abstract

A medical case of early onset and severe course of juvenile ankylosing spondylitis and eyes involvement resistant to routine immunosuppressive drugs is represented in this article. The successful treatment with biological agent adalimumab is described. By the 4th week of treatment the acute inflammatory changes in joints have been arrested, the motion capacity completely restored. By the 8th week of treatment the remission of uveitis has been confirmed, the laboratory indicators of active stage of disease (ESR, serum CRP) have been normalized.

Keywords

• children
• ankylosingspondylitis
• uveitis
• adalimumab