Nature Communications (Apr 2021)

Production of itaconic acid from alkali pretreated lignin by dynamic two stage bioconversion

  • Joshua R. Elmore,
  • Gara N. Dexter,
  • Davinia Salvachúa,
  • Jessica Martinez-Baird,
  • E. Anne Hatmaker,
  • Jay D. Huenemann,
  • Dawn M. Klingeman,
  • George L. Peabody,
  • Darren J. Peterson,
  • Christine Singer,
  • Gregg T. Beckham,
  • Adam M. Guss

DOI
https://doi.org/10.1038/s41467-021-22556-8
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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Lignin conversion to higher value products is essential to the economic viability of lignocellulosic biorefineries. Here, the authors demonstrate the bioconversion of alkali pretreated lignin to itaconic acid by dynamic two stage fermentation using a signal-amplified nitrogen-limitation biosensor.