Epidermolysis bullosa acquisita

Abstract

The article describes present-day information on the pathogenesis, clinical picture, treatment and differential diagnostics of epidermolysis bullosa acquisita, an autoimmune skin disease caused by the production of anti-Type VII collagen autoantibodies and manifested mainly by subepidermal blisters and erosions. The authors present the results of a case study of a rare form of epidermolysis bullosa - epidermolysis bullosa acquisita in a male patient aged 53. A combined therapy with peroral prednisolone and subcutaneous injections of methotrexate had a positive effect in the form of epithelialization of most of the erosions.

Keywords

• приобретенный буллезный эпидермолиз
• дифференциальная диагностика
• непрямая реакция иммунофлюоресценции
• epidermolysis bullosa acquisita
• differential diagnostics
• indirect immunofluorescence