Frontiers in Medicine (Jan 2022)
Clinical Characteristics and Early Visual Outcomes of Highly Myopic Cataract Eyes: The Shanghai High Myopia Study
- Wenwen He,
- Wenwen He,
- Wenwen He,
- Wenwen He,
- Yunqian Yao,
- Yunqian Yao,
- Yunqian Yao,
- Yunqian Yao,
- Keke Zhang,
- Keke Zhang,
- Keke Zhang,
- Keke Zhang,
- Yu Du,
- Yu Du,
- Yu Du,
- Yu Du,
- Jiao Qi,
- Jiao Qi,
- Jiao Qi,
- Jiao Qi,
- Yinglei Zhang,
- Yinglei Zhang,
- Yinglei Zhang,
- Yinglei Zhang,
- Shaohua Zhang,
- Shaohua Zhang,
- Shaohua Zhang,
- Shaohua Zhang,
- Zhennan Zhao,
- Zhennan Zhao,
- Zhennan Zhao,
- Zhennan Zhao,
- Lei Cai,
- Lei Cai,
- Lei Cai,
- Lei Cai,
- Qi Fan,
- Qi Fan,
- Qi Fan,
- Qi Fan,
- Yongxiang Jiang,
- Yongxiang Jiang,
- Yongxiang Jiang,
- Yongxiang Jiang,
- Jin Yang,
- Jin Yang,
- Jin Yang,
- Jin Yang,
- Xiangjia Zhu,
- Xiangjia Zhu,
- Xiangjia Zhu,
- Xiangjia Zhu,
- Yi Lu,
- Yi Lu,
- Yi Lu,
- Yi Lu
Affiliations
- Wenwen He
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Wenwen He
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Wenwen He
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Wenwen He
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Yunqian Yao
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Yunqian Yao
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Yunqian Yao
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Yunqian Yao
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Keke Zhang
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Keke Zhang
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Keke Zhang
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Keke Zhang
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Yu Du
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Yu Du
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Yu Du
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Yu Du
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Jiao Qi
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Jiao Qi
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Jiao Qi
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Jiao Qi
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Yinglei Zhang
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Yinglei Zhang
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Yinglei Zhang
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Yinglei Zhang
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Shaohua Zhang
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Shaohua Zhang
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Shaohua Zhang
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Shaohua Zhang
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Zhennan Zhao
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Zhennan Zhao
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Zhennan Zhao
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Zhennan Zhao
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Lei Cai
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Lei Cai
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Lei Cai
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Lei Cai
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Qi Fan
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Qi Fan
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Qi Fan
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Qi Fan
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Yongxiang Jiang
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Yongxiang Jiang
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Yongxiang Jiang
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Yongxiang Jiang
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Jin Yang
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Jin Yang
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Jin Yang
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Jin Yang
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Xiangjia Zhu
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Xiangjia Zhu
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Xiangjia Zhu
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Xiangjia Zhu
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- Yi Lu
- Department of Ophthalmology, Eye Institute, Eye & ENT Hospital, Fudan University, Shanghai, China
- Yi Lu
- NHC Key Laboratory of Myopia (Fudan University), Shanghai, China
- Yi Lu
- Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China
- Yi Lu
- Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China
- DOI
- https://doi.org/10.3389/fmed.2021.671521
- Journal volume & issue
-
Vol. 8
Abstract
Purpose: To report ocular characteristics and early visual outcomes of highly myopic cataract eyes, and to analyze the risk factors of low vision.Methods: A total of 2,027 eyes of 1,400 cataract patients with axial length (AL) ≥ 26 mm undergoing cataract surgery in Eye & ENT Hospital of Fudan University, who were registered in the Shanghai High Myopia Study, were analyzed. Routine pre-operative ophthalmic examinations were performed and macular scan of optical coherence tomography (OCT) were obtained. Macular complications, central foveal thickness (CFT) and subfoveal choroidal thickness (SFCT) were evaluated from OCT images. Ocular and surgical history and perioperative complications were also recorded. Uncorrected and best-corrected visual acuity (UCVA/BCVA) 1 month post-operatively and its influencing factors were evaluated.Results: The average AL of all involved eyes was 29.52 ± 2.26 mm, and 39.7% of which were with an AL > 30 mm and 26.4% of which were with a corneal astigmatism more than 1.5 D. Nuclear cataract accounted for the largest proportion (70.6%). The rate of overall macular complications was 27.6%. Postoperative UCVA and BCVA were 0.70 ± 0.46 and 0.25 ± 0.32 logMAR, respectively. BCVA improved significantly after surgery (vs. P < 0.001) and affected by the elongation of AL (P < 0.001) and thinning of CFT and SFCT (both P < 0.001). The risk factors of post-operative low vision (BCVA < 20/66) were macular atrophy, lamellar macular hole, high corneal astigmatism, long AL, thin SFCT and junior surgeons, odds ratios ranging from 1.54 to 54.87 (all P < 0.05).Conclusion: Cataract surgery could improve the VA of highly myopic eyes. Eye with macular complications, higher corneal astigmatism, longer AL, thinner SFCT, and who was treated by a junior surgeon, may have a high risk of low vision after surgery.
Keywords
