P442: DDX41 GERMLINE VARIANTS: POPULATION PREVALENCE, SIGNIFICANCE AND LEUKEMIC EVOLUTION

• Sruthi Cheloor Kovilakam,
• Muxin Gu,
• William G. Dunn,
• Ludovica Marando,
• Clea Barcena,
• Serena Nik Zainal,
• Irina Mohorianu,
• Siddhartha P. Kar,
• Margarete A. Fabre,
• Pedro M. Quiros,
• George S. Vassiliou

Affiliations

Sruthi Cheloor Kovilakam

1 University of Cambridge, Department of Haematology, Cambridge, United Kingdom

Muxin Gu

2 University of Cambridge, Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom

William G. Dunn

2 University of Cambridge, Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom

Ludovica Marando

2 University of Cambridge, Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom

Clea Barcena

1 University of Cambridge, Department of Haematology, Cambridge, United Kingdom

Serena Nik Zainal

4 University of Cambridge, Early Cancer Institute, Department of Oncology, United Kingdom

Irina Mohorianu

2 University of Cambridge, Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom

Siddhartha P. Kar

4 University of Cambridge, Early Cancer Institute, Department of Oncology, United Kingdom

Margarete A. Fabre

7 AstraZeneca, Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, Cambridge, United Kingdom

Pedro M. Quiros

1 University of Cambridge, Department of Haematology, Cambridge, United Kingdom

George S. Vassiliou

1 University of Cambridge, Department of Haematology, Cambridge, United Kingdom