Research progress in corrosion resistance and biocompatibility of strontium-containing coatings on medical metal surface

Abstract

With the progress of global population aging and the incidence rate of bone and joint diseases, the demand for bone repair medical metal materials is increasing.Bio-metallic materials include non-degradable (i.e. titanium) and degradable metals (i.e. magnesium and iron). However, metals are insufficient in corrosion resistance and osseointegration, so their surface modification needs to be optimized. It is noted that strontium (Sr) has the effect of promoting osteogenesis and inhibiting osteoclasts, and thus the use of Sr as a modified component is of great significance for improving the activity of bone cells on biomedical metal surfaces. In this paper, the corrosion resistance and biocompatibility of strontium doped coatings on titanium, magnesium and iron in recent years were summarized and compared.This article focuses on the research on improving the osseointegration performance of composite coatings prepared by combining strontium and carriers with good degradability and biocompatibility(such as hydroxyapatite, brushite, etc.) on the surface of titanium alloy, magnesium alloy and iron alloy. Finally, it is believed that the application of strontium-containing coatings on the surface of metal materials has a wide range of prospects, and it was proposed that the combination of strontium and zinc make the metal materials have antibacterial properties while promoting bone repair.It was expected to provide reference for promising clinical applications of strontium-doped coating.

Keywords

• biomaterial
• strontium
• coating
• bone repair
• corrosion resistance
• biocompatibility