391 A first-in-human study of intratumoral SAR441000, an mRNA mixture encoding IL-12sc, interferon alpha2b, GM-CSF and IL-15sushi as monotherapy and in combination with cemiplimab in advanced solid tumors

• Evelyna Derhovanessian,
• Nicolas Acquavella,
• Christophe Massard,
• Carmen Loquai,
• Jochen Utikal,
• Jean-Francois Baurain,
• Oliver Bechter,
• Marie-Laure Ozoux,
• Rahul Marpadga,
• Esteban-Rodrigo Imedio

Affiliations

Evelyna Derhovanessian

Aff1 grid.411544.10000000101968249Department of Internal Medicine II, Section for Transplantation Immunology and ImmunohaematologyUniversity Hospital Tuebingen Germany

Nicolas Acquavella

Aff562 grid.26790.3a0000000419368606Sylvester Comprehensive Cancer CenterUniversity of Miami Miami FL USA

Christophe Massard

5Institut de Cancérologie Gustave Roussy, Villejuif, France

Carmen Loquai

Department of Dermatology, Johannes Gutenberg University Hospital Mainz, Mainz, Germany

Jochen Utikal

2Heidelberg University, Mannheim, Germany

Jean-Francois Baurain

7Université Catholique de Louvain and Cliniques Universitaires Saint-Luc

Oliver Bechter

1University Hospitals Leuven, Leuven, Belgium

Marie-Laure Ozoux

6Sanofi Research and Development, Cambridge, MA, USA

Rahul Marpadga

6Sanofi Research and Development, Cambridge, MA, USA

Esteban-Rodrigo Imedio

5BioNTech, Mainz, Germany