THE RELATIONSHIP BETWEEN ABO BLOOD GROUP AND ATRIAL FIBRILLATION

Abstract

Atrial fibrillation is the most common type of cardiac arrhythmia associated with substantial mortality and morbidity, largely due to thromboembolism, particularly stroke. AF shares strong association with cardiovascular diseases like hypertension, ischemic heart disease, congestive heart failure, valvular heart disease. Although almost all risks of AF have been overlooked but correlation between ABO blood group and AF in general has not been investigated. Hence, we decided to study and identify the link between ABO blood group and AF. To fully assess effects of ABO blood group on AF and investigate the interaction between blood groups and sex on the prevalence of atrial fibrillation. This is a retrospective descriptive cross-sectional study. The data originates from database of "Scientific Research Institute of Cardiology and Internal Diseases" Almaty city, Kazakhstan during 2019. AF was confirmed using an electrocardiograph. IBM SPSS version 22 was used to conduct the statistical analyses. Тhere were 475 patients with atrial fibrillation included in this study. A total of 279 patients (58.7%) were male, and 196 patients (41.3%) were female. The distribution of ABO blood group in the patients was as follows: 165 patients had blood group A (34.7%), 112 patients had blood group B (23.6%), 52 patients had blood group AB (10.9%) and 146 patients had blood group O (30.7%). After comparison of O blood group with non O blood groups there was no significant difference in number of O and A blood groups (P = 0.282), but other non O blood groups had significant differences in number [B (P = 0.035), AB (P = 0,000)]. Оur results establish that non-O blood groups act as an independent risk factor for AF compared with individuals having O type blood.

Keywords

• atrial fibrillation
• abo blood group