Communicating hydrocephalus and coexisting nonenhancing tumor: An ominous sign for patients with neurofibromatosis type 1?

Ryo Miyahara, MD; Satoshi Tsutsumi, MD; Satoshi Adachi, MD; Hisato Ishii, MD; Akihide Kondo, MD; Yukimasa Yasumoto, MD

Radiology Case Reports (Jun 2018)

Communicating hydrocephalus and coexisting nonenhancing tumor: An ominous sign for patients with neurofibromatosis type 1?

Ryo Miyahara, MD,
Satoshi Tsutsumi, MD,
Satoshi Adachi, MD,
Hisato Ishii, MD,
Akihide Kondo, MD,
Yukimasa Yasumoto, MD

Affiliations

Ryo Miyahara, MD: Department of Neurological Surgery, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan
Satoshi Tsutsumi, MD: Department of Neurological Surgery, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan; Corresponding author.
Satoshi Adachi, MD: Department of Neurological Surgery, Juntendo University School of Medicine, Tokyo, Japan
Hisato Ishii, MD: Department of Neurological Surgery, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan
Akihide Kondo, MD: Department of Neurological Surgery, Juntendo University School of Medicine, Tokyo, Japan
Yukimasa Yasumoto, MD: Department of Neurological Surgery, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan

Journal volume & issue: Vol. 13, no. 3
pp. 693 – 696

Abstract

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A 26-year-old woman with familial neurofibromatosis type 1 sustained headache that worsened for 1 month. Neuroimaging revealed a mild ventriculomegaly and nonenhancing lesion in the pons. In spite of repeated cerebrospinal fluid examinations and magnetic resonance imaging, the etiology was not determined. The affected pons markedly enlarged in the following 2 months, with extensive leptomeningeal dissemination. Biopsy through hemilaminectomy of the T9 was diagnosed as glioblastoma multiforme. Prompt histologic examination should be performed when patients with familial neurofibromatosis type 1 manifest communicating hydrocephalus coexistent with a nonenhancing tumor. Keywords: Communicating hydrocephalus, Nonenhancing pontine tumor, Leptomeningeal GBM, Neurofibromatosis type 1

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: http://www.journals.elsevier.com/radiology-case-reports/

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