Abstracts from the 3rd International Severe Asthma Forum (ISAF)

• M. E. Ketelaar,
• K. Van De Kant,
• F. N. Dijk,
• E. M. M. Klaassen,
• N. Grotenboer,
• M. C. Nawijn,
• E. Dompeling,
• G. H. Koppelman,
• Clare Murray,
• Philip Foden,
• Lesley Lowe,
• Hannah Durrington,
• Adnan Custovic,
• Angela Simpson,
• Andrew J. Simpson,
• Dominick E. Shaw,
• Ana R. Sousa,
• Louise J. Fleming,
• Graham Roberts,
• Ioannis Pandis,
• Aruna T. Bansal,
• Julie Corfield,
• Scott Wagers,
• Ratko Djukanovic,
• Kian Fan Chung,
• Peter J. Sterk,
• Jorgen Vestbo,
• Stephen J. Fowler,
• S. J. Tebbutt,
• A. Singh,
• C. P. Shannon,
• Y. W. Kim,
• C. X. Yang,
• G. M. Gauvreau,
• J. M. Fitzgerald,
• L. P. Boulet,
• P. M. O’Byrne,
• N. Begley,
• A. Loudon,
• D. W. Ray,
• Selene Baos,
• Lucía Cremades,
• David Calzada,
• Carlos Lahoz,
• Blanca Cárdaba,
• Kewal Asosingh,
• Chris Lauruschkat,
• Kimberly Queisser,
• Nicholas Wanner,
• Kelly Weiss,
• Weiling Xu,
• Serpil Erzurum,
• Milena Sokolowska,
• Li-Yuan Chen,
• Yueqin Liu,
• Asuncion Martinez-Anton,
• Carolea Logun,
• Sara Alsaaty,
• Rosemarie Cuento,
• Rongman Cai,
• Junfeng Sun,
• Oswald Quehenberger,
• Aaron Armando,
• Edward Dennis,
• Stewart Levine,
• James Shelhamer,
• Kilyong Choi,
• Snezhina Lazova,
• Penka Perenovska,
• Dimitrinka Miteva,
• Stamatios Priftis,
• Guergana Petrova,
• Vassil Yablanski,
• Evgeni Vlaev,
• Hristina Rafailova,
• Takashi Kumae,
• L. J. Holmes,
• J. Yorke,
• D. M. Ryan,
• Sasawan Chinratanapisit,
• Khlongtip Matchimmadamrong,
• Jitladda Deerojanawong,
• Wissaroot Karoonboonyanan,
• Paskorn Sritipsukho,
• Vania Youroukova,
• Denitsa Dimitrova,
• Yanina Slavova,
• Spaska Lesichkova,
• Iren Tzocheva,
• Snezhana Parina,
• Svetla Angelova,
• Neli Korsun,
• Mihai Craiu,
• Iustina Violeta Stan,
• Matea Deliu,
• Tolga Yavuz,
• Matthew Sperrin,
• Umit M. Sahiner,
• Danielle Belgrave,
• Cansin Sackesen Sackesen,
• Ömer Kalayci,
• Petar Velikov,
• Tsvetelina Velikova,
• Ekaterina Ivanova-Todorova,
• Kalina Tumangelova-Yuzeir,
• Dobroslav Kyurkchiev,
• Spyridon Megremis,
• Bede Constantinides,
• Alexandros Georgios Sotiropoulos,
• Paraskevi Xepapadaki,
• David Robertson,
• Nikolaos Papadopoulos,
• Maxim Wilkinson,
• Craig Portsmouth,
• David Ray,
• Royston Goodacre,
• Anna Valerieva,
• Irina Bobolea,
• Daiana Guillén Vera,
• Gabriel Gonzalez-Salazar,
• Carlos Melero Moreno,
• Consuelo Fernandez Rodriguez,
• Natividad De Las Cuevas Moreno,
• R. Wang,
• I. Satia,
• R. Niven,
• J. A. Smith,
• T. Southworth,
• J. Plumb,
• V. Gupta,
• J. Pearson,
• I. Ramis,
• M. D. Lehner,
• M. Miralpeix,
• D. Singh,
• Imran Satia,
• Mark Woodhead,
• Paul O’Byrne,
• Jaclyn Ann Smith,
• Cecilia Forss,
• Peter Cook,
• Sheila Brown,
• Freya Svedberg,
• Katherine Stephenson,
• Margherita Bertuzzi,
• Elaine Bignell,
• Malin Enerbäck,
• Danen Cunoosamy,
• Andrew Macdonald,
• Caini Liu,
• Liang Zhu,
• Kiochi Fukuda,
• Cunjin Zhang,
• Suidong Ouyang,
• Xing Chen,
• Luke Qin,
• Suguna Rachakonda,
• Mark Aronica,
• Jun Qin,
• Xiaoxia Li,
• Marie-Chantal Larose,
• Anne-Sophie Archambault,
• Véronique Provost,
• Jamila Chakir,
• Michel Laviolette,
• Nicolas Flamand,
• Nicola Logan,
• Dominik Ruckerl,
• Judith E. Allen,
• Tara E. Sutherland,
• E. Hamelmann,
• C. Vogelberg,
• S. Goldstein,
• G. E. Azzi,
• M. Engel,
• R. Sigmund,
• S. J. Szefler,
• Raquel Mesquita,
• Luis Coentrão,
• Rui Veiga,
• José-Artur Paiva,
• Roberto Roncon-Albuquerque,
• Wendy Vargas Porras,
• Ana González Moreno,
• Jesus Macías Iglesias,
• Gustavo Córdova Ramos,
• Yesenia Peña Acevedo,
• Miguel Angel Tejedor Alonso,
• Maria Del Mar Moro Moro,
• Irena Krcmova,
• Jakub Novosad,
• Nicola Alexander Hanania,
• Marc Massanari,
• Heike Hecker,
• Eric Kassel,
• Craig Laforce,
• Kathy Rickard,
• Sanne Snelder,
• Gert-Jan Braunstahl,
• T. L. Jones,
• D. Neville,
• E. R. Heiden,
• E. Lanning,
• T. Brown,
• H. Rupani,
• K. S. Babu,
• A. J. Chauhan,
• M. Y. Eldegeir,
• A. A. Chapman,
• M. Ferwana,
• M. Caldron

Affiliations

M. E. Ketelaar

Beatrix Children’s Hospital, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen

K. Van De Kant

Department of Pediatric Pulmonology, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Center (MUMC+)

F. N. Dijk

Beatrix Children’s Hospital, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen

E. M. M. Klaassen

Department of General Practice, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Center (MUMC+)

N. Grotenboer

Department of Pathology and Medical Biology, Laboratory of Experimental Pulmonology and Inflammation Research (EXPIRE), Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen

M. C. Nawijn

Department of Pathology and Medical Biology, Laboratory of Experimental Pulmonology and Inflammation Research (EXPIRE), Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen

E. Dompeling

Department of Pediatric Pulmonology, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Center (MUMC+)

G. H. Koppelman

Beatrix Children’s Hospital, Groningen Research Institute for Asthma and COPD (GRIAC), University Medical Center Groningen

Clare Murray

University of Manchester

Philip Foden

University of Manchester

Lesley Lowe

University of Manchester

Hannah Durrington

University of Manchester

Adnan Custovic

Imperial College

Angela Simpson

University of Manchester

Andrew J. Simpson

Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester and University Hospital of South Manchester, NHS Foundation Trust

Dominick E. Shaw

Respiratory Research Unit, University of Nottingham

Ana R. Sousa

Respiratory Therapeutic Unit, GSK

Louise J. Fleming

National Heart and Lung Institute, Imperial College

Graham Roberts

Biomedical Research Unit, Clinical and Experimental Sciences and Human Development and Health, NIHR Southampton Respiratory

Ioannis Pandis

Data Science Institute, South Kensington Campus, Imperial College London

Aruna T. Bansal

Acclarogen Ltd, St John’s Innovation Centre

Julie Corfield

AstraZeneca R&D

Scott Wagers

BioSci Consulting

Ratko Djukanovic

Biomedical Research Unit, Clinical and Experimental Sciences and Human Development and Health, NIHR Southampton Respiratory

Kian Fan Chung

National Heart and Lung Institute, Imperial College

Peter J. Sterk

Dept of Respiratory Medicine, Academic Medical Centre, University of Amsterdam

Jorgen Vestbo

Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, The University of Manchester and University Hospital of South Manchester, NHS Foundation Trust

Stephen J. Fowler

University of Manchester

S. J. Tebbutt

University of British Columbia

A. Singh

University of British Columbia

C. P. Shannon

PROOF Centre of Excellence

Y. W. Kim

University of British Columbia

C. X. Yang

University of British Columbia

G. M. Gauvreau

McMaster University

J. M. Fitzgerald

University of British Columbia

L. P. Boulet

Université Laval

P. M. O’Byrne

McMaster University

N. Begley

University of Manchester

A. Loudon

University of Manchester

D. W. Ray

University of Manchester

Selene Baos

IIS-Fundación Jiménez Díaz-UAM

Lucía Cremades

IIS-Fundación Jiménez Díaz-UAM

David Calzada

IIS-Fundación Jiménez Díaz-UAM

Carlos Lahoz

IIS-Fundación Jiménez Díaz-UAM

Blanca Cárdaba

IIS-Fundación Jiménez Díaz-UAM

Kewal Asosingh

Cleveland Clinic

Chris Lauruschkat

Cleveland Clinic

Kimberly Queisser

Cleveland Clinic

Nicholas Wanner

Cleveland Clinic

Kelly Weiss

Cleveland Clinic

Weiling Xu

Cleveland Clinic

Serpil Erzurum

Cleveland Clinic

Milena Sokolowska

Critical Care Medicine Department, Clinical Center, NIH

Li-Yuan Chen

Critical Care Medicine Department, Clinical Center, NIH

Yueqin Liu

Critical Care Medicine Department, Clinical Center, NIH

Asuncion Martinez-Anton

Critical Care Medicine Department, Clinical Center, NIH

Carolea Logun

Critical Care Medicine Department, Clinical Center, NIH

Sara Alsaaty

Critical Care Medicine Department, Clinical Center, NIH

Rosemarie Cuento

Laboratory of Asthma and Lung Inflammation, Cardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, NIH

Rongman Cai

Critical Care Medicine Department, Clinical Center, NIH

Junfeng Sun

Critical Care Medicine Department, Clinical Center, NIH

Oswald Quehenberger

Department of Medicine, Department of Pharmacology

Aaron Armando

Department of Chemistry and Biochemistry

Edward Dennis

Department of Chemistry and Biochemistry

Stewart Levine

Laboratory of Asthma and Lung Inflammation, Cardiovascular and Pulmonary Branch, National Heart, Lung and Blood Institute, NIH

James Shelhamer

Critical Care Medicine Department, Clinical Center, NIH

Kilyong Choi

Seoul Medical Center

Snezhina Lazova

Medical University, Pediatric Clinic, UMHAT Alexandrovska

Penka Perenovska

Medical University, Pediatric Clinic, UMHAT Alexandrovska

Dimitrinka Miteva

Medical University, Pediatric Clinic, UMHAT Alexandrovska

Stamatios Priftis

Medical University

Guergana Petrova

Medical University, Pediatric Clinic, UMHAT Alexandrovska

Vassil Yablanski

Orthopedics Department, Tokuda Hospital

Evgeni Vlaev

Orthopedics Department, Tokuda Hospital

Hristina Rafailova

Medical University, Pediatric Clinic, UMHAT Alexandrovska

Takashi Kumae

Research Institute, Tokyo University of Agriculture

L. J. Holmes

University Hospital of South Manchester & University of Manchester

J. Yorke

University of Manchester

D. M. Ryan

University Hospital of South Manchester

Sasawan Chinratanapisit

Division of Allergy and Immunology, Department of Pediatrics, Bhumibol Adulyadej Hospital

Khlongtip Matchimmadamrong

Saraburi Hospital

Jitladda Deerojanawong

Division of Respiratory Disease and Intensive Care, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University

Wissaroot Karoonboonyanan

Department of Pediatrics, Bhumibol Adulyadej Hospital

Paskorn Sritipsukho

Center of Excellence in Applied Epidemiology, Thammasat University

Vania Youroukova

Clinical Center of Pulmonary Diseases; SHATPD “St. Sofia”, Medical Faculty of Medical University of Sofia

Denitsa Dimitrova

Clinical Center of Pulmonary Diseases; SHATPD “St. Sofia”, Medical Faculty of Medical University of Sofia

Yanina Slavova

Clinical Center of Pulmonary Diseases; SHATPD “St. Sofia”, Medical Faculty of Medical University of Sofia

Spaska Lesichkova

Department of Clinical Immunology, Medical Faculty of Medical University of Sofia, University Hospital Alexandrovska

Iren Tzocheva

Pediatric Clinic, University Hospital Alexandrovska, Medical University

Snezhana Parina

Pediatric Clinic, University Hospital Alexandrovska, Medical University

Svetla Angelova

National Centre of Infectious and Parasitic Diseases, National Laboratory Influenza and ARD

Neli Korsun

National Centre of Infectious and Parasitic Diseases, National Laboratory Influenza and ARD

Mihai Craiu

INSMC Alessandrescu-Rusescu

Iustina Violeta Stan

INSMC Alessandrescu-Rusescu

Matea Deliu

Institute of Population Health, Health e-Research Centre, University of Manchester

Tolga Yavuz

Division of Pediatric Allergy, GATA Military School of Medicine

Matthew Sperrin

Centre for Health Informatics, Institute of Population Health, University of Manchester

Umit M. Sahiner

Division of Pediatric Allergy, Hacettepe University School of Medicine

Danielle Belgrave

Faculty of Medicine, Department of Medicine, Imperial College London

Cansin Sackesen Sackesen

Koç University Hospital

Ömer Kalayci

Pediatric Allergy and Asthma Unit, Hacettepe University School of Medicine

Petar Velikov

Medical University

Tsvetelina Velikova

Laboratory of Clinical Immunology, University Hospital St. Ivan Rilski, Medical University

Ekaterina Ivanova-Todorova

Laboratory of Clinical Immunology, University Hospital St. Ivan Rilski, Medical University

Kalina Tumangelova-Yuzeir

Laboratory of Clinical Immunology, University Hospital St. Ivan Rilski, Medical University

Dobroslav Kyurkchiev

Laboratory of Clinical Immunology, University Hospital St. Ivan Rilski, Medical University

Spyridon Megremis

University of Manchester

Bede Constantinides

University of Manchester

Alexandros Georgios Sotiropoulos

University of Manchester

Paraskevi Xepapadaki

University of Athens

David Robertson

University of Manchester

Nikolaos Papadopoulos

University of Manchester

Maxim Wilkinson

Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester

Craig Portsmouth

Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester

David Ray

Division of Metabolism and Gastroenterology, Faculty of Biology, Medicine and Health, University of Manchester

Royston Goodacre

School of Chemistry, Manchester Institute of Biotechnology, University of Manchester

Anna Valerieva

Clinic of Allergy and Asthma, University Hospital Alexandrovska, Medical Faculty of Medical University of Sofia

Irina Bobolea

Hospital 12 de octubre, i+12 Research Institute

Daiana Guillén Vera

Hospital 12 de octubre, i+12 Research Institute

Gabriel Gonzalez-Salazar

Hospital 12 de octubre, i+12 Research Institute

Carlos Melero Moreno

Hospital 12 de octubre, i+12 Research Institute

Consuelo Fernandez Rodriguez

Hospital 12 de octubre, i+12 Research Institute

Natividad De Las Cuevas Moreno

Hospital 12 de octubre, i+12 Research Institute

R. Wang

University Hospital of South Manchester

I. Satia

University Hospital of South Manchester

R. Niven

University Hospital of South Manchester

J. A. Smith

University Hospital of South Manchester

T. Southworth

University of Manchester

J. Plumb

University of Manchester

V. Gupta

University of Manchester

J. Pearson

University of Manchester

I. Ramis

Almirall S. A.

M. D. Lehner

Almirall S. A.

M. Miralpeix

Almirall S. A.

D. Singh

University of Manchester

Imran Satia

University of Manchester

Mark Woodhead

University of Manchester

Paul O’Byrne

McMaster University

Jaclyn Ann Smith

University of Manchester

Cecilia Forss

Manchester Collaborative Centre for Inflammation Research

Peter Cook

Manchester Collaborative Centre for Inflammation Research

Sheila Brown

Manchester Collaborative Centre for Inflammation Research

Freya Svedberg

Manchester Collaborative Centre for Inflammation Research

Katherine Stephenson

Manchester Collaborative Centre for Inflammation Research

Margherita Bertuzzi

Manchester Fungal Infection Group

Elaine Bignell

Manchester Fungal Infection Group

Malin Enerbäck

AstraZeneca R&D

Danen Cunoosamy

AstraZeneca R&D

Andrew Macdonald

Manchester Collaborative Centre for Inflammation Research

Caini Liu

Cleveland Clinic

Liang Zhu

Cleveland Clinic

Kiochi Fukuda

Cleveland Clinic

Cunjin Zhang

Cleveland Clinic

Suidong Ouyang

Cleveland Clinic

Xing Chen

Cleveland Clinic

Luke Qin

Cleveland Clinic

Suguna Rachakonda

Cleveland Clinic

Mark Aronica

Cleveland Clinic

Jun Qin

Cleveland Clinic

Xiaoxia Li

Cleveland Clinic

Marie-Chantal Larose

CRIUCPQ

Anne-Sophie Archambault

CRIUCPQ

Véronique Provost

CRIUCPQ

Jamila Chakir

CRIUCPQ

Michel Laviolette

CRIUCPQ

Nicolas Flamand

CRIUCPQ

Nicola Logan

Institute of Immunology and Infection Research, University of Edinburgh

Dominik Ruckerl

Faculty of Biology, Medicine & Health, University of Manchester

Judith E. Allen

Faculty of Biology, Medicine & Health, University of Manchester

Tara E. Sutherland

Manchester Collaborative Centre for Inflammation Research, University of Manchester

E. Hamelmann

Children’s Center, Evangelisches Krankenhaus Bielefeld, and Allergy Center, Ruhr University

C. Vogelberg

University Hospital Carl Gustav Carus, Technical University of Dresden

S. Goldstein

Island Medical Research, Rockville Centre

G. E. Azzi

Boehringer Ingelheim Pharma GmbH & Co. KG

M. Engel

Boehringer Ingelheim Pharma GmbH & Co. KG

R. Sigmund

Boehringer Ingelheim Pharma GmbH & Co. KG

S. J. Szefler

Children’s Hospital of Colorado, University of Colorado School of Medicine

Raquel Mesquita

Internal Medicine Department, Centro Hospitalar de São João

Luis Coentrão

Emergency and Intensive Care Medicine Department, Centro Hospitalar de São João

Rui Veiga

Emergency and Intensive Care Medicine Department, Centro Hospitalar de São João

José-Artur Paiva

Emergency and Intensive Care Medicine Department, Centro Hospitalar de São João

Roberto Roncon-Albuquerque

Emergency and Intensive Care Medicine Department, Centro Hospitalar de São João

Wendy Vargas Porras

University Hospital Foundation Alcorcón

Ana González Moreno

University Hospital Foundation Alcorcón

Jesus Macías Iglesias

University Hospital Foundation Alcorcón

Gustavo Córdova Ramos

University Hospital Foundation Alcorcón

Yesenia Peña Acevedo

University Hospital Foundation Alcorcón

Miguel Angel Tejedor Alonso

University Hospital Foundation Alcorcón

Maria Del Mar Moro Moro

University Hospital Foundation Alcorcón

Irena Krcmova

Institute of Clinical Immunology and Allergy, University Hospital

Jakub Novosad

Institute of Clinical Immunology and Allergy, University Hospital

Nicola Alexander Hanania

Baylor College of Medicine

Marc Massanari

Circassia

Heike Hecker

Circassia

Eric Kassel

Circassia

Craig Laforce

North Carolina Clinical Research

Kathy Rickard

Circassia

Sanne Snelder

Sint Franciscus Gasthuis

Gert-Jan Braunstahl

Sint Franciscus Gasthuis

T. L. Jones

Portsmouth Hospitals NHS Trust

D. Neville

Portsmouth Hospitals NHS Trust

E. R. Heiden

Portsmouth Hospitals NHS Trust

E. Lanning

Portsmouth Hospitals NHS Trust

T. Brown

Portsmouth Hospitals NHS Trust

H. Rupani

Portsmouth Hospitals NHS Trust

K. S. Babu

Portsmouth Hospitals NHS Trust

A. J. Chauhan

Portsmouth Hospitals NHS Trust

M. Y. Eldegeir

National Guard Hospital

A. A. Chapman

Imperial College

M. Ferwana

King Saud University

M. Caldron

Imperial College