Severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infections occurring in healthcare workers after booster vaccination: A comparison of delta versus omicron variants

Kimberly D. Reeves; Christopher M. Polk; Laura A. Cox; Robert T. Fairman; Gregory A. Hawkins; Catherine L. Passaretti; Mindy M. Sampson

doi:10.1017/ash.2022.239

Antimicrobial Stewardship & Healthcare Epidemiology (Jan 2022)

Severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infections occurring in healthcare workers after booster vaccination: A comparison of delta versus omicron variants

Kimberly D. Reeves,
Christopher M. Polk,
Laura A. Cox,
Robert T. Fairman,
Gregory A. Hawkins,
Catherine L. Passaretti,
Mindy M. Sampson

Affiliations

Kimberly D. Reeves: Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolia Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina
Christopher M. Polk: ORCiD; Division of Infection Diseases, Department of Medicine, Atrium Health, Charlotte, North Carolina
Laura A. Cox: ORCiD; Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolia Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina
Robert T. Fairman: ORCiD; Division of Infection Diseases, Department of Medicine, Atrium Health, Charlotte, North Carolina Department of Health Policy & Behavioral Sciences, School of Public Health, Georgia State University, Atlanta, Georgia
Gregory A. Hawkins: Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolia Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina
Catherine L. Passaretti: ORCiD; Division of Infection Diseases, Department of Medicine, Atrium Health, Charlotte, North Carolina
Mindy M. Sampson: ORCiD; Division of Infection Diseases, Department of Medicine, Atrium Health, Charlotte, North Carolina

DOI: https://doi.org/10.1017/ash.2022.239
Journal volume & issue: Vol. 2

Abstract

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In this study, we used genomic sequencing to identify variants of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) in healthcare workers with coronavirus disease 2019 (COVID-19) after receiving a booster vaccination. We compared symptoms, comorbidities, exposure risks, and vaccine history between the variants. Postbooster COVID-19 cases increased as the SARS-CoV-2 omicron variant predominated.

Published in Antimicrobial Stewardship & Healthcare Epidemiology

ISSN: 2732-494X (Online)
Publisher: Cambridge University Press
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases; Medicine: Public aspects of medicine
Website: https://www.cambridge.org/core/journals/antimicrobial-stewardship-and-healthcare-epidemiology

About the journal