mBio (Jun 2021)

Loss of the Bacterial Flagellar Motor Switch Complex upon Cell Lysis

  • Mohammed Kaplan,
  • Elitza I. Tocheva,
  • Ariane Briegel,
  • Megan J. Dobro,
  • Yi-Wei Chang,
  • Poorna Subramanian,
  • Alasdair W. McDowall,
  • Morgan Beeby,
  • Grant J. Jensen

DOI
https://doi.org/10.1128/mBio.00298-21
Journal volume & issue
Vol. 12, no. 3

Abstract

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The bacterial flagellar motor is a complex macromolecular machine whose function and self-assembly present a fascinating puzzle for structural biologists. Here, we report that in diverse bacterial species, cell lysis leads to loss of the cytoplasmic switch complex and associated ATPase before other components of the motor.