Journal of Nepal Medical Association (Oct 2003)
SUBACUTE CUTANEOUS LUPUS ERYTHEMATOSUS WITH PSEUDO-PORPHYRIA AND VITILIGO
Abstract
Sub acute Cutaneous Lupus Erythematosus (SCLE) is a distinct subset of Lupus Erythematosus. It can present as non scarring psoriasiform or annular polycyclic lesions. About half the patients fulfil the criteria of the American Rheumatism Association for systemic lupus erythematosus. In this report, we present the case of a 45 years old male who came with psoriasiform depigmented plaques and papulo-vesicular lesions developed after taking some medication. Clinically diagnosed as sub acute cutaneous lupus erythematosus with acral vitiligo. A histopathological study and urine analysis however revealed presence of pseudo porphyria along with the SCLE. Although SCLE is not a rare disease, the association of it with pseudo porphyria and vitiligo is of significance as the treatment for SCLE and pseudo porphyria is photo protection and for the vitiligo it is photo chemotherapy. ABSTRACT Key Words: Sub acute cutaneous lupus erythematosus, pseudo porphyria, vitiligo, psoriasiform eruptions.