Effects of lithium ascorbate in middle-aged patients with stenosing atherosclerosis of brachiocephalic arteries

Abstract

Resume. Lithium ascorbate is a highly digestible and low-toxic lithium salt. In stis study patients with stenosing arteriosclerosis of brachiocephalic arteries were under observation (n = 70, mean age 52 years, 50 % men). In group A (n = 30), participants received standard therapy and lithium ascorbate (0.78 mg/day of elemental lithium, 8 weeks), in group B (n = 40, control) - only the standard therapy. Effects of the lithium ascorbate on the results of neuropsychological testing (Luria's technique, Schulte tables, MMSE and BDI scales, visual-spatial gnosis), levels of BDNF and the levels of trace elements in hair have been established. Lithium ascorbate contributed to a significant improvement in work capacity, mood, a decrease in the proportion of patients with 20 % cerebral stenosis, increased levels of BDNF and a decrease in the levels of toxic trace elements in the hair.

Keywords

• церебральный атеросклероз
• bdnf
• микроэлементы
• аскорбат лития
• cerebral atherosclerosis
• bdnf
• microelements
• lithium ascorbate