Copy number variation-associated lncRNAs may contribute to the etiologies of congenital heart disease

Yibo Lu; Qing Fang; Ming Qi; Xiaoliang Li; Xingyu Zhang; Yuwan Lin; Ying Xiang; Qihua Fu; Bo Wang

doi:10.1038/s42003-023-04565-z

Communications Biology (Feb 2023)

Copy number variation-associated lncRNAs may contribute to the etiologies of congenital heart disease

Yibo Lu,
Qing Fang,
Ming Qi,
Xiaoliang Li,
Xingyu Zhang,
Yuwan Lin,
Ying Xiang,
Qihua Fu,
Bo Wang

Affiliations

Yibo Lu: Pediatric Translational Medicine Institute, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University
Qing Fang: Pediatric Translational Medicine Institute, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University
Ming Qi: Pediatric Translational Medicine Institute, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University
Xiaoliang Li: Department of Medical Genetics and Molecular Diagnostic Laboratory, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University
Xingyu Zhang: Pediatric Translational Medicine Institute, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University
Yuwan Lin: Pediatric Translational Medicine Institute, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University
Ying Xiang: Pediatric Translational Medicine Institute, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University
Qihua Fu: Pediatric Translational Medicine Institute, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University
Bo Wang: Pediatric Translational Medicine Institute, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University

DOI: https://doi.org/10.1038/s42003-023-04565-z
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 16

Abstract

Read online

A transcriptomic analysis of lncRNAs within copy-number variations identifies HSALNG0104472 as a potential lncRNA effector of cardiac defects in non-syndromic congenital heart disease.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal