Cytokines and Chemokines in Irritant Contact Dermatitis

Haur Yueh Lee; Marco Stieger; Nikhil Yawalkar; Masato Kakeda

doi:10.1155/2013/916497

Mediators of Inflammation (Jan 2013)

Cytokines and Chemokines in Irritant Contact Dermatitis

Haur Yueh Lee,
Marco Stieger,
Nikhil Yawalkar,
Masato Kakeda

Affiliations

Haur Yueh Lee: Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland
Marco Stieger: Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland
Nikhil Yawalkar: Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland
Masato Kakeda: Department of Dermatology, Inselspital, University of Bern, 3010 Bern, Switzerland

DOI: https://doi.org/10.1155/2013/916497
Journal volume & issue: Vol. 2013

Abstract

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Irritant contact dermatitis is a result of activated innate immune response to various external stimuli and consists of complex interplay which involves skin barrier disruption, cellular changes, and release of proinflammatory mediators. In this review, we will focus on key cytokines and chemokines involved in the pathogenesis of irritant contact dermatitis and also contrast the differences between allergic contact dermatitis and irritant contact dermatitis.

Published in Mediators of Inflammation

ISSN: 0962-9351 (Print); 1466-1861 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Pathology
Website: https://onlinelibrary.wiley.com/journal/4792

About the journal