Alzheimer‘s disease: exploring nature’s ‘medicinal chest’ for new therapeutic agents

Abstract

Natural products have served humanity as a valuable source for the discovery and development of therapeutic agents. In addition, these phytochemicals can function as lead compounds for the development of synthetic analogs aimed at treating human diseases. In our aging society, Alzheimer’s disease (AD) is the most common cause of dementia, which is characterized by a significant and progressive loss of memory and other cognitive functions. As society demographics change, the predominance of AD and other age-related dementias is increasing, with concurrent financial and societal costs.

Keywords

• alzheimer’s disease
• natural products
• amyloidogenesis
• protein aggregation inhibitors
• crocus sativus l