Metabolite trafficking enables membrane-impermeable-terpene secretion by yeast

So-Hee Son; Jae-Eung Kim; Gyuri Park; Young-Joon Ko; Bong Hyun Sung; Jongcheol Seo; Seung Soo Oh; Ju Young Lee

doi:10.1038/s41467-022-30312-9

Nature Communications (May 2022)

Metabolite trafficking enables membrane-impermeable-terpene secretion by yeast

So-Hee Son,
Jae-Eung Kim,
Gyuri Park,
Young-Joon Ko,
Bong Hyun Sung,
Jongcheol Seo,
Seung Soo Oh,
Ju Young Lee

Affiliations

So-Hee Son: Research Center for Bio-based Chemistry, Korea Research Institute of Chemical Technology (KRICT)
Jae-Eung Kim: Research Center for Bio-based Chemistry, Korea Research Institute of Chemical Technology (KRICT)
Gyuri Park: Department of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH)
Young-Joon Ko: Research Center for Bio-based Chemistry, Korea Research Institute of Chemical Technology (KRICT)
Bong Hyun Sung: Synthetic Biology and Bioengineering Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB)
Jongcheol Seo: Department of Chemistry, Pohang University of Science and Technology (POSTECH)
Seung Soo Oh: School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology (POSTECH)
Ju Young Lee: Research Center for Bio-based Chemistry, Korea Research Institute of Chemical Technology (KRICT)

DOI: https://doi.org/10.1038/s41467-022-30312-9
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 9

Abstract

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The engineering of metabolite secretion from microorganisms can lead to many applications in synthetic biology. In this article, the authors engineer a metabolite trafficking system for the secretion of medicinal terpenes.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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