Semiology and clinical development of cystopathy in patients with type 2 diabetes mellitus

Abstract

Aim. To investigate clinical peculiarities of cystopathy in correlation with duration of type 2 diabetes mellitus (T2DM). Materials and Methods. 70 patients with T2DM (26 male and 44 female; mean age 63.3?4.2) were monitored under this study. Pres- ence, form and severity of diabetic dysfunction of lower urinary tract were evaluated based on natural history, complains, physical examination, urination records and urodynamic testing. Results. Clinical and urodynamic evidence for cystopathy was obtained in 61 participant (87.1%). 32 patients (45.7%) demonstrated signs of overactive bladder, while 29 (41.4%) had underactive bladder syndrome (UBS). We observed three stages in the development of diabetic cytopathy: latent stage followed by overactive bladder (in 5 years from first signs of T2DM) and finally by UBS (in 10 years, respectively). Conclusion. Our data shows association between clinical picture of diabetic cystopathy and duration of T2DM.

Keywords

• diabetes mellitus
• diabetic cystopathy
• overactive bladder
• underactive bladder syndrome