ANGIOTENSIN CONVERTING ENZYME INHIBITORS AND ANGIOTENSIN RECEPTOR BLOCKERS: IS THERE A REASON TO CONSIDER AN EQUIVALENCE OF TWO DRUG CLASSES FROM THE EVIDENCE BASED MEDICINE STANDPOINT

Abstract

The results of the main large controlled trials that had proven effect of ACE inhibitors (ACEi) and angiotensin receptor blockers (ARB) on cardiovascular diseases outcomes are evaluated. Data of the recent meta-analyzes comparing ACEi and ARB effects on the life prognosis in patients of the high cardiovascular risk are presented. Better validity of ACEi efficacy versus this of ARB is concluded.

Keywords

• ингибиторы ангиотензинпревращающего фермента
• антагонисты рецепторов ангиотензина
• отдаленные результаты лечения