Baqai Journal of Health Sciences (Jul 2024)
RELATIONSHIP BETWEEN INCIDENCE OF BREAST CARCINOMA AND FIRSTDEGREE RELATIVE POSITIVITY
Abstract
Objective: This study aims to find out a relationship between incidence of breast carcinoma & first degree relative positivity. Methodology: A case control study was conducted to compare the Ca breast patients with positive first degree relative (group A) to Ca breast patients having negative first degree family relative positivity (group B), alongside the presence of secondary malignancies. Patients of age groupof 20-70 were assessed clinically with in the hospital outpatient department (OPD) setting from 2017 to 2023. The diagnosed cases were filtered, using the triple parameters (mammogram, fnac/trucut or physical asses.A Pre-prepared questionnaire was used to collect the initial information and patients were asked to follow up post treatment to continue the momentum. Results: The total numbers of participants partaking this research study were 158 in number. However, the highest incidence of first degree relative positivity was noted in 45-60years of age being about 5 first degree positive cases in 64 primary cases while the lowest was recorded in 20-30 years of age being null in 5 primary cases .The secondary malignancies were lowest in 20-30 at about 7 among the 5 primary cases and peaked at 60-70 and >70 age group being about 13 incidences among 29 primary cases. Albeit, al l age groups lacked daughter being the positive first degree relative. Conclusion: Presence of first degree family relative strongly influences the incidence of breast Ca and as well as the secondary malignancies that manifest 60 years of Age above. The age group (45 till 60 yrs) as being the highest percentage of first degree relative positivity should be screened biannually.
