Bacteriological studies of new substituted hydroxy -1, 3-propanediones and 4-methyl-5-chloroacetophenones

Abstract

The titled compounds were screened for antibacterial activity against gram + & gram – bacteria such as Escherichia coli, Bacillus subtilis, Staphylococcus aureus, and Pseudomonas aeruginosa, Proteus vulgaris and Enterobacter aerogenes by using Muller Hinton Hiveg Agar No.2 MV-1084 (Hi-Media). All the screened compounds were found inactive against Bacillus subtilis, Enterobacter aerogenes and Escherichia coli. The produced compounds have shown average to good antibacterial activity

Keywords

• hydroxy-1,3-propanediones
• antibacterial activity
• chloroacetophenones