Proceedings (Apr 2019)

Hydroquinone-Derivatives Induce Cell Death in Chronic Myelogenous Leukemia

  • Sungmi Song,
  • Claudia Cerella,
  • Barbora Orlikova-Boyer,
  • Ali Al-Mourabit,
  • Marc Diederich

DOI
https://doi.org/10.3390/proceedings2019011028
Journal volume & issue
Vol. 11, no. 1
p. 28

Abstract

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Hydroquinone (HQ) is a phenolic metabolite of benzene, which is used as a skin whitener. Insects synthesize this natural compound as a deterrent and mushrooms as a toxin. Pro-apoptotic effects of HQ were previously documented on various cancer cell types. Here we investigated the cell-death inducing mechanisms of this compound in chronic myeloid leukemia cell models.

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