Ionotropic receptors mediate nitrogenous waste avoidance in Drosophila melanogaster

Subash Dhakal; Jiun Sang; Binod Aryal; Youngseok Lee

doi:10.1038/s42003-021-02799-3

Communications Biology (Nov 2021)

Ionotropic receptors mediate nitrogenous waste avoidance in Drosophila melanogaster

Subash Dhakal,
Jiun Sang,
Binod Aryal,
Youngseok Lee

Affiliations

Subash Dhakal: Department of Bio and Fermentation Convergence Technology, Kookmin University
Jiun Sang: Department of Bio and Fermentation Convergence Technology, Kookmin University
Binod Aryal: Department of Bio and Fermentation Convergence Technology, Kookmin University
Youngseok Lee: Department of Bio and Fermentation Convergence Technology, Kookmin University

DOI: https://doi.org/10.1038/s42003-021-02799-3
Journal volume & issue: Vol. 4, no. 1
pp. 1 – 10

Abstract

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Dhakal et al. use chemoreceptor screening on three ionotropic receptors in Drosophila, IR25a, IR76b, IR51b to evaluate their impact on avoidance behaviors against nitrogenous waste products. The results of electrophysiology assays show that ammonia compounds are aversive in taste by directly activating bitter-sensing gustatory receptor neurons.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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