Nature Communications (Jun 2020)

Quantifying molecular bias in DNA data storage

  • Yuan-Jyue Chen,
  • Christopher N. Takahashi,
  • Lee Organick,
  • Callista Bee,
  • Siena Dumas Ang,
  • Patrick Weiss,
  • Bill Peck,
  • Georg Seelig,
  • Luis Ceze,
  • Karin Strauss

DOI
https://doi.org/10.1038/s41467-020-16958-3
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 9

Abstract

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DNA is an attractive digital data storing medium due to high information density and longevity. Here the authors use millions of sequences to investigate inherent biases in DNA synthesis and PCR amplification.