International Journal of Molecular Sciences (Jan 2023)

Nature-Inspired Surface Structures Design for Antimicrobial Applications

  • Meng-Shiue Lee,
  • Hussein Reda Hussein,
  • Sheng-Wen Chang,
  • Chia-Yu Chang,
  • Yi-Ying Lin,
  • Yueh Chien,
  • Yi-Ping Yang,
  • Lik-Voon Kiew,
  • Ching-Yun Chen,
  • Shih-Hwa Chiou,
  • Chia-Ching Chang

DOI
https://doi.org/10.3390/ijms24021348
Journal volume & issue
Vol. 24, no. 2
p. 1348

Abstract

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Surface contamination by microorganisms such as viruses and bacteria may simultaneously aggravate the biofouling of surfaces and infection of wounds and promote cross-species transmission and the rapid evolution of microbes in emerging diseases. In addition, natural surface structures with unique anti-biofouling properties may be used as guide templates for the development of functional antimicrobial surfaces. Further, these structure-related antimicrobial surfaces can be categorized into microbicidal and anti-biofouling surfaces. This review introduces the recent advances in the development of microbicidal and anti-biofouling surfaces inspired by natural structures and discusses the related antimicrobial mechanisms, surface topography design, material application, manufacturing techniques, and antimicrobial efficiencies.

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