Clinical, Cosmetic and Investigational Dermatology (Sep 2022)
Cutaneous Metastasis from Lung Adenocarcinoma
Abstract
Lingzhi Zhong, Dandan Mao, Houmin Li, Xue Chen, Jiang Jin, Guangdong Wen Department of Dermatology, Peking University People’s Hospital, Beijing, People’s Republic of ChinaCorrespondence: Guangdong Wen, Peking University People’s Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, People’s Republic of China, Tel +86-10-88325472, Email [email protected]: Cutaneous metastases are rare and often portend the aggressive malignancy and poor prognosis. We report a case of a 62-year-old man with a rapidly growing nodule on the left back for 2 months. The patient was diagnosed with lung adenocarcinoma shortly before the skin lesion presented. Physical examination showed a dome-shaped purplish red nodule, with ulceration and hemorrhagic crust. Excision of the skin lesion was performed, and the histopathology showed tumor cells infiltrate with immunohistochemistry (TTF-1+CK7+CD20–) favoring primary lung adenocarcinoma.Keywords: cutaneous metastases, lung cancer, adenocarcinoma, immunohistochemistry, case report
