A novel nanocomposite based on mycosynthesized bimetallic zinc-copperoxide nanoparticles, nanocellulose and chitosan: Characterization, antimicrobial and photocatalytic activities

Abstract

Background: Recently, nanomaterials have received much attention due to their important role in solving medical and environmental problems. In the present study, a novel nanocomposite based on mycosynthesized bimetallic zinc-copper oxides nanoparticles, nanocellulose, and chitosan was ready through an ecofriendly method. Characterization, antimicrobial and photocatalytic activities were evaluated. Results: The result revealed that the prepared nanocomposite exhibited antibacterial activity against Bacillus subtilis, Escherichia coli and Staphylococcus aureus, where MICs were 7.81, 31.25 and 62.5 µg mL−1. As well, the nanocomposite showed potential antifungal activity against Aspergillus brasiliensis where MIC was 7.81 µg mL−1, but had minimal antifungal efficacy against Cryptococcus neoformans and Candida albicans where the MIC was 250 µg mL−1 for each other. Furthermore, the nanocomposite had photocatalytic activity. The bimetallic and nanocomposite materials were characterized via physiochemical and topographic analysis. Conclusions: In conclusion, the prepared nanocomposite based on mycosynthesized bimetallic zinc-copper oxides nanoparticles nanocellulose and chitosan has antimicrobial and photocatalytic activities which can be applied to various environments.How to cite: Hasanin MS, Hashem AH, Al-Askar AA, et al. A novel nanocomposite based on mycosynthesized bimetallic zinc-copper oxides nanoparticles, nanocellulose and chitosan: Characterization, antimicrobial and photocatalytic activities. Electron J Biotechnol 2023;65. https://doi.org/10.1016/j.ejbt.2023.05.001.

Keywords

• Antimicrobial activity
• Bimetallic zinc-copper oxides nanoparticles
• Candida albicans
• Chitosan
• Cryptococcus neoformans
• Mycosynthesis