Significance of perilesional T1 hyperintense areas in the differential diagnosis of primary adult-type diffuse glioma: A case report

Akinari Yamano, MD; Kiyoyuki Yanaka, MD, PhD; Kuniyuki Onuma, MD; Kazuhiro Nakamura, MD, PhD; Nobuyuki Takahashi, MD, PhD; Hidehiro Kohzuki, MD, PhD; Noriaki Sakamoto, MD, PhD; Masahide Matsuda, MD, PhD; Eiichi Ishikawa, MD, PhD

Radiology Case Reports (Oct 2023)

Significance of perilesional T1 hyperintense areas in the differential diagnosis of primary adult-type diffuse glioma: A case report

Akinari Yamano, MD,
Kiyoyuki Yanaka, MD, PhD,
Kuniyuki Onuma, MD,
Kazuhiro Nakamura, MD, PhD,
Nobuyuki Takahashi, MD, PhD,
Hidehiro Kohzuki, MD, PhD,
Noriaki Sakamoto, MD, PhD,
Masahide Matsuda, MD, PhD,
Eiichi Ishikawa, MD, PhD

Affiliations

Akinari Yamano, MD: Department of Neurosurgery, Tsukuba Memorial Hospital, Tsukuba, Ibaraki, Japan; Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan
Kiyoyuki Yanaka, MD, PhD: Department of Neurosurgery, Tsukuba Memorial Hospital, Tsukuba, Ibaraki, Japan
Kuniyuki Onuma, MD: Department of Neurosurgery, Tsukuba Memorial Hospital, Tsukuba, Ibaraki, Japan
Kazuhiro Nakamura, MD, PhD: Department of Neurosurgery, Tsukuba Memorial Hospital, Tsukuba, Ibaraki, Japan
Nobuyuki Takahashi, MD, PhD: Department of Radiology, Tsukuba Memorial Hospital, Tsukuba City, Ibaraki, Japan
Hidehiro Kohzuki, MD, PhD: Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan
Noriaki Sakamoto, MD, PhD: Department of Pathology, Faculty of Medicine, University of Tsukuba, Tsukuba City, Ibaraki, Japan
Masahide Matsuda, MD, PhD: Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan
Eiichi Ishikawa, MD, PhD: Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, 2-1-1 Amakubo, Tsukuba, Ibaraki, 305-8576, Japan; Corresponding author.

Journal volume & issue: Vol. 18, no. 10
pp. 3448 – 3452

Abstract

Read online

Perilesional T1 hyperintensity on magnetic resonance imaging (MRI) of intra-axial brain masses is an unusual feature of the perilesional area, characteristic of cavernous malformations (CMs) and metastatic brain tumors (METs). Here, we report a case of primary diffuse glioma with a perilesional T1 hyperintense area (HIA) on MRI. A 61-year-old woman with transient aphasia visited our hospital. Radiological examination revealed an intra-axial mass with acute/subacute hemorrhaging and calcification in the left frontal lobe. It was presumed to be a CM because of the perilesional T1 HIA. Gross total resection of the tumor was performed, and the pathological diagnosis was anaplastic oligodendroglioma, not otherwise specified by World Health Organization 2016 classification. Histopathological findings in the perilesional T1 HIA indicated hemorrhage involvement in the surrounding white matter. No recurrence appeared after radio-chemotherapy. Perilesional T1 HIAs, characteristic of CMs and METs, are also seen in primary diffuse gliomas. Therefore, caution should be taken when using this sign for the differential diagnosis of intracranial masses.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: https://www.sciencedirect.com/journal/radiology-case-reports

About the journal

Abstract

Keywords