Communications Biology (Aug 2022)

Optogenetic manipulation of cell migration with high spatiotemporal resolution using lattice lightsheet microscopy

  • Wei-Chun Tang,
  • Yen-Ting Liu,
  • Cheng-Han Yeh,
  • Chieh-Han Lu,
  • Chiao-Hui Tu,
  • Yi-Ling Lin,
  • Yu-Chun Lin,
  • Tsui-Ling Hsu,
  • Liang Gao,
  • Shu-Wei Chang,
  • Peilin Chen,
  • Bi-Chang Chen

DOI
https://doi.org/10.1038/s42003-022-03835-6
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 11

Abstract

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Using a Bessel beam as a simulation source allows the use of lattice lightsheet microscopy for spatiotemporal control of photoactivation, illustrated by the control of cellular migration behavior.