Hypoglycemic potential of Momordica charantia Linn in Streptozotocin induced diabetic Albino mice

Abstract

In order to check hypoglycemic property of Momordica charantia, experiments were conducted in streptozotocin induced diabetic albino mice. The LD50 of STZ was seen to be 650 mg/kg bw. Significant reduction in blood glucose level was seen within 24 hours after administration of ethanolic extract of MC. On administration of subsequent doses of ethanolic extract, significant decrease has also been seen in serum glucose level, creatinine, ALT, AST, AP of STZ induced albino mice. Thus one or other part of MC can be used in lowering down blood glucose level.

Keywords

• Glucose
• Kidney function
• Liver function
• Momordica charantia