Vestnik Dermatologii i Venerologii (Aug 2017)
Efficiency and tolerance of acne therapy using system isotretinoin
- Yu. N. Perlamutrov,
- K. B. Olkhovskaya,
- M. M. Kokhan,
- Yu. V. Keniksfest,
- Yu. B. Shaibakova,
- N. V. Polyakova,
- E. P. Topychkanova,
- Ya. V. Kashcheeva,
- A. V. Samtsov,
- A. V. Statsenko,
- I. E. Belousova,
- V. R. Khayrutdinov,
- S. V. Volkova,
- A. S. Zhukov
Affiliations
- Yu. N. Perlamutrov
- State Budgetary Educational Institution “A.I. Evdokimov Moscow State Medical and Denatal University”
- K. B. Olkhovskaya
- State Budgetary Educational Institution “A.I. Evdokimov Moscow State Medical and Denatal University”
- M. M. Kokhan
- Federal State Budgetary Institution “Ural Scientific and Research Institute of Dermatoveneriology and immunopathology” of the Ministry of Health of Russia
- Yu. V. Keniksfest
- Federal State Budgetary Institution “Ural Scientific and Research Institute of Dermatoveneriology and immunopathology” of the Ministry of Health of Russia
- Yu. B. Shaibakova
- Federal State Budgetary Institution “Ural Scientific and Research Institute of Dermatoveneriology and immunopathology” of the Ministry of Health of Russia
- N. V. Polyakova
- Federal State Budgetary Institution “Ural Scientific and Research Institute of Dermatoveneriology and immunopathology” of the Ministry of Health of Russia
- E. P. Topychkanova
- Federal State Budgetary Institution “Ural Scientific and Research Institute of Dermatoveneriology and immunopathology” of the Ministry of Health of Russia
- Ya. V. Kashcheeva
- Federal State Budgetary Institution “Ural Scientific and Research Institute of Dermatoveneriology and immunopathology” of the Ministry of Health of Russia
- A. V. Samtsov
- Federal State Budgetary Educational Institution Higher Professional Education “S.M. Kirov Military and Medical Academy”
- A. V. Statsenko
- Federal State Budgetary Educational Institution Higher Professional Education “S.M. Kirov Military and Medical Academy”
- I. E. Belousova
- Federal State Budgetary Educational Institution Higher Professional Education “S.M. Kirov Military and Medical Academy”
- V. R. Khayrutdinov
- Federal State Budgetary Educational Institution Higher Professional Education “S.M. Kirov Military and Medical Academy”
- S. V. Volkova
- Federal State Budgetary Educational Institution Higher Professional Education “S.M. Kirov Military and Medical Academy”
- A. S. Zhukov
- Federal State Budgetary Educational Institution Higher Professional Education “S.M. Kirov Military and Medical Academy”
- DOI
- https://doi.org/10.25208/0042-4609-2015-0-5-128-133
- Journal volume & issue
-
Vol. 0,
no. 5
pp. 128 – 133
Abstract
Purpose. Determination of efficiency and tolerance of Sotret product in treatment of patients with different clinical forms and severe acne in three clinical investigations. Materials and methods. 103 patients with acne (moderate and severe acne, acne conglobata and acne inversa) were examined and treated. All patients underwent monotherapy with Sotret with clinical effectiveness assessment and records of adverse events. Results. Sotret therapy facilitated clinical remission of acne in 90-100% of cases. Adverse events were easily tolerated and were not serious. Conclusion. Established therapeutic efficiency of Sotret determines its potential in treating various severity and various forms of acne.
Keywords
- акне средней и тяжелой степени тяжести
- конглобатные акне
- инверсные акне
- изотретиноин
- сотрет
- достижение клинической ремиссии
- низкий риск серьезных нежелательных явлений
- moderate and severe acne
- acne conglobate
- acne inversa
- isotretinoin
- sotret
- achieving clinical remission
- low risk of serious adverse events
