Radiology Case Reports (Jan 2025)

FES avid pulmonary adenocarcinoma and confounding ER+ breast carcinoma

  • Yousif M. Abdelmoneim, MD,
  • Yanyan Lou, MD PhD,
  • Pooja Advani, MD,
  • Andras Khoor, MD PhD,
  • Akash Sharma, MD,
  • Ephraim E. Parent, MD PhD

Journal volume & issue
Vol. 20, no. 1
pp. 801 – 804

Abstract

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Breast carcinomas are well known for expression of estrogen receptor (ER) however there are other malignancies that are also express ER, possibly confounding the diagnostic interpretation of 16α-[18F]fluoro-17β-estradiol (FES; Cerianna GE HealthCare) in patients with both ER+ breast carcinomas and other malignancies. We present a case of a woman with prior history of both ER+ breast carcinoma and pulmonary adenocarcinoma with subsequent identification of an FES pulmonary nodule that was proven on histopathology to be consistent with an ER expressing pulmonary adenocarcinoma metastasis

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