Malignant gliomas: old and new systemic treatment approaches

Abstract

Malignant (high-grade) gliomas are rapidly progressive brain tumours with very high morbidity and mortality. Until recently, treatment options for patients with malignant gliomas were limited and mainly the same for all subtypes of malignant gliomas. The treatment included surgery and radiotherapy. Chemotherapy used as an adjuvant treatment or at recurrence had a marginal role.

Keywords

• malignant gliomas
• systemic treatment
• multidisciplinary
• survival
• quality of life