Polymer Testing (Jan 2021)

Insight into the morphology, pore structure and sorption properties of 4-hydroxy-3-nitrophenylacetic acid imprinted poly(acrylic acid-co-ethylene glycol dimethacrylate) sorbent

  • Marta Janczura,
  • Monika Sobiech,
  • Piotr Luliński

Journal volume & issue
Vol. 93
p. 106983

Abstract

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In this paper the exploration of specific imprinted sorbent for 4-hydroxy-3-nitrophenylacetic acid (NHPA), an indicator of 3-nitrotyrosine, a biomarker of pathophysiological states, was described. The optimization of synthetic protocol, supported by theoretical studies, allowed to select NHPA imprinted poly(acrylic acid-co-ethylene glycol dimethacrylate) as the most specific polymer with imprinting factor equal to 2.27. The acrylic copolymers were characterized, revealing differences between the imprinted and non-imprinted material in the adsorption binding capacities (0.54 ± 0.12 and 0.335 ± 0.073 μmol g−1, respectively), heterogeneity indices (0.47 and 0.72), pseudo-second order kinetics constants (0.251 and 0.077 g μmol −1 min−1, respectively), and total specific surface areas (51.8 and 292.3 m2 g−1, respectively). The significant difference in the microstructure of pores was considered as the crucial factor responsible for sorption properties of analyzed materials.

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