Detection of pathogenic bacteria with special emphasis to biosensors integrated with AuNPs

Abstract

Bacteria are unambiguously menacing for community healthiness globally. The common reservoirs of bacteria are contaminated foods, animals, polluted water and soil. There are several diseases causing bacteria such as Vibrio, Listeria, Yersinia, Salmonella, Shigella, Clostridium, Campylobacter and many more. The apprehension for the transmission of bacterial infection has increased the incidence of outbreaks and several health issues across boundaries. The key challenge for treatment of bacterial infection in early stage is the investigation of multiplexed bacterial virulent factors. Therefore, it requisites the development of highly efficient techniques to identify, prevent and manage growth of pathogenic bacteria for the well-being of living system. Conventional techniques including serological tests, immuno assays, polymerase chain reaction (PCR) and isothermal microcalorimetry (IMC) and many other techniques have been used for the testing of bacterial infection. However limitations of aforesaid techniques have been overcome by biosensing techniques as they have offered numerous advantages including highly simple, sensitive, specific, cost effective and quick response generating reproducible, on-site detection and ease of portability. Present review article deciphers the role of distinct types of biosensors based on gold nanoparticles for the analysis of bacteria from different reservoirs.

Keywords

• Bacterial infection
• Nanotechnology
• AuNPs
• Biosensors
• Bacterial infections