Linchuang shenzangbing zazhi (Jan 2015)
Efficacy of Shengxuening tablets combined with erythropoietin in treatment of renal anemia of diabetic kidney disease stage V patients
Abstract
Objective To observe the efficacy of Shengxuening tablets combined with erythropoietin in treatment of renal anemia of diabetic kidney disease stage V patients.Methods Sixty patients with stage-V diabetic kidney disease were randomly divided into treatment group and control group.The treatment group was given Shengxuening tablets combined with erythropoietin,and the control group given ferrous succinate combined with erythropoietin.The patients were followed up for 3 months.Hemoglobin(Hb),hematocrit(Hct),serum ferritin(SF),and transferrin saturation(TSAT) were detected before and after the treatment The indexes of ALT,SCr and K~+ were detected before and after the treatment Results The efficacy in the treatment group was more satisfactory than the control group.The total effective rate in the control group was 83.3%,and that in the treatment group reached 90%(P0.05).Conclusions The effect of Shengxuening combined with erythropoietin in treating renal anemia of stage-V diabetic nephropathy is evident.Shengxuening combined with erythropoietin can significantly increase hemoglobin(Hb),Hct,serum iron(SF) and transferrin saturation(TAST) levels,improve the iron metabolism and correct the renal anemia,but has no significant impact on liver function,renal function and serum potassium.Shengxuening combined with erythropoietin is safe and effective,and has less adverse reaction.
