Naphthalimide Based Al3+-Selective Fluorescent Probe and its Use in Cell Imaging

Abstract

A new naphthalimide derivative was synthesized and characterized as Al3+-selective fluorescent probe. Study showed that this probe has good affinity and sensitibity towards Al3+ compared to other common metal ions, and the addition of Al3+ triggered a prominent fluorescence enhancement at 439 nm in ethanol phase. With the optimized experimental conditions, the probe exhibited a dynamic response range for Al3+ from 1.0´10-6 M to 5.0´10-6 M with a detection limit of 4.1´10-7 M.

Keywords

• Fluorescent probe
• Al3+
• Schiff base
• Cell imaging
• Synthesis.