Selagibenzophenone B and Its Derivatives: SelB‑1, a Dual Topoisomerase I/II Inhibitor Identified through In Vitro and In Silico Analyses

• Serhat Dönmez,
• Ringaile Lapinskaite,
• Hazal Nazlican Atalay,
• Esra Tokay,
• Feray Kockar,
• Lukas Rycek,
• Mehmet Özbil,
• Tugba Boyunegmez Tumer

Affiliations

Serhat Dönmez

Graduate Program of Molecular Biology and Genetics, School of Graduate Studies, Canakkale Onsekiz Mart University, Canakkale, Turkey

Ringaile Lapinskaite

Department of Organic Chemistry, Center for Physical Sciences and Technology (FTMC), Vilnius, Lithuania

Hazal Nazlican Atalay

Graduate Program of Molecular Biology and Genetics, School of Graduate Studies, Canakkale Onsekiz Mart University, Canakkale, Turkey

Esra Tokay

Department of Molecular Biology and Genetics, Faculty of Sciences and Arts, Balikesir University, Balikesir, Turkey

Feray Kockar

Department of Molecular Biology and Genetics, Faculty of Sciences and Arts, Balikesir University, Balikesir, Turkey

Lukas Rycek

Department of Organic Chemistry, Faculty of Science, Charles University, Praha 2, Czechia

Mehmet Özbil

Institute of Biotechnology, Gebze Technical University, Kocaeli, Turkey

Tugba Boyunegmez Tumer

Department of Molecular Biology and Genetics, Faculty of Science, Canakkale Onsekiz Mart University, Canakkale, Turkey