Data on the effects of Glochidion zeylanicum leaf extracts in Caenorhabditis elegans
Chatrawee Duangjan,
Panthakarn Rangsinth,
Xiaojie Gu,
Shaoxiong Zhang,
Michael Wink,
Tewin Tencomnao
Affiliations
Chatrawee Duangjan
Graduate Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand; Institute of Pharmacy and Molecular Biotechnology, Im Neuenheimer Feld 364, Heidelberg University, 69120, Heidelberg, Germany; Age-Related Inflammation and Degeneration Research Unit, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand
Panthakarn Rangsinth
Graduate Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand; Institute of Pharmacy and Molecular Biotechnology, Im Neuenheimer Feld 364, Heidelberg University, 69120, Heidelberg, Germany; Age-Related Inflammation and Degeneration Research Unit, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand
Xiaojie Gu
Department of Biotechnology, School of Environmental and Chemical Engineering, Dalian Jiaotong University, Dalian, 116028, China; Institute of Pharmacy and Molecular Biotechnology, Im Neuenheimer Feld 364, Heidelberg University, 69120, Heidelberg, Germany
Shaoxiong Zhang
College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou, 350002, China; Institute of Pharmacy and Molecular Biotechnology, Im Neuenheimer Feld 364, Heidelberg University, 69120, Heidelberg, Germany
Michael Wink
Institute of Pharmacy and Molecular Biotechnology, Im Neuenheimer Feld 364, Heidelberg University, 69120, Heidelberg, Germany; Corresponding author.
Tewin Tencomnao
Graduate Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand; Age-Related Inflammation and Degeneration Research Unit, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand; Corresponding author. Age-Related Inflammation and Degeneration Research Unit, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
The present article contains the data on the effects of Glochidion zeylanicum leaf extracts in C. elegans, which is related to the article '' Glochidion zeylanicum leaf extracts exhibit lifespan extending and oxidative stress resistance properties in Caenorhabditis elegans via DAF-16/FoxO and SKN-1/Nrf-2 signaling pathways'' Chatrawee et al., 2019. This dataset was generated to better understand the antioxidant and anti-aging properties of G. zeylanicum leaf extracts in C. elegans. The bioactive compounds of the extracts were analyzed using GLC-MS, LC-MS, and RP-HPLC. The antioxidant properties were determined using phenolics, flavonoids, ABTS and DPPH assays. The in vivo antioxidant properties were performed using the intracellular ROS accumulation and the survival rate under oxidative stress condition assays. The brood size, body length and life-span were determined regarding anti-aging properties in this data. Keywords: Glochidion zeylanicum, Caenorhabditis elegans, Antioxidants, Aging, GLC-MS, LC-MS, RP-HPLC
