Ensemble Classifier Based on Interval Modeling for Microarray Datasets

Abstract

The purpose of the study is to propose a multi-class ensemble classifier using interval modeling dedicated to microarray datasets. An approach of creating the uncertainty intervals for the single prediction values of constituent classifiers and then aggregating the obtained intervals with the use of interval-valued aggregation functions is used. The proposed heterogeneous classification employs Random Forest, Support Vector Machines, and Multilayer Perceptron as component classifiers, utilizing cross-entropy to select the optimal classifier. Moreover, orders for intervals are applied to determine the decision class of an object. The applied interval-valued aggregation functions are tested in terms of optimizing the performance of the considered ensemble classifier. The proposed model’s quality, superior to other well-known and component classifiers, is validated through comparison, demonstrating the efficacy of cross-entropy in ensemble model construction.

Keywords

• multi-class classification
• microarrays
• ensemble classification
• entropy
• cross-entropy
• aggregation functions