Revista da Sociedade Brasileira de Medicina Tropical (Nov 2021)

Systemic inflammatory syndrome in children during COVID-19 pandemic in Ceará state, northeastern Brazil: an observational study

  • Luís Arthur Brasil Gadelha Farias,
  • Magda Moura de Almeida,
  • Pâmela Maria Costa Linhares,
  • Bruno Cavalcante Fales de Brito Alves,
  • Roberto Jorge Colares Duarte Filho,
  • Roberio Dias Leite,
  • Marco Aurelio Palazzi Safadi,
  • Luciano Pamplona de Góes Cavalcanti

DOI
https://doi.org/10.1590/0037-8682-0383-2021
Journal volume & issue
Vol. 54

Abstract

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Abstract In this study, we report the occurrence of multisystemic inflammatory syndrome among 64 children (2 deaths) with recent severe acute respiratory syndrome-related coronavirus 2 (SARS-COV-2) infections in the northeast region of Brazil. The major clinical symptoms and signs reported were exanthema (60.9%), abdominal pain (56.3%), nausea and vomiting (46.9%), diarrhea (37.5%), and dyspnea (37.5%). Laboratory findings revealed that the levels of C-reactive protein (75.0%), hemoglobin (51.6%), D-dimer (48.4%), lymphocytes (43.8%), LDH (45.3%), AST (42.2%), ALT (51.6%), and ferritin (48.4%) were above the reference values for a given age and gender. The clinical findings were similar to those observed in Kawasaki disease, although it represents a separate entity, emphasizing the need for proactive surveillance and early treatment.

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