Sensitivity and specificity of the detection of spondylodiscitis by conventional radiography

Abstract

Objective: Diagnosis of spondylodiscitis is usually possible radiographically with magnetic resonance imaging (MRI). However, the first imaging method evaluated in daily practice is conventional radiography. The aim of the study was to determine the sensitivity and specificity of detecting infectious or rheumatological spondylodiscitis in the lumbar region with conventional radiography by rheumatologists. Methods: Among 102 patients with spondylodiscitis on lumbosacral (LS) MRI, 23 patients who also underwent simultaneous conventional LS radiography were included. TThe control group consisted of 52 outpatients with no evidence of spondylodiscitis on LS MRI. Eleven rheumatologists blindly evaluated conventional LS radiographs. Sensitivity, specificity, positive, and negative predictive values of LS conventional radiography were calculated. Results: While the cause was infection in 8/23 (34.7%) of spondylodiscitis patients, it was spondyloarthritis in 15/23 (65.2%). According to LS MRI findings, 23 patients had spondylodiscitis in a total of 31 vertebral units. When we evaluated the detection of spondylodiscitis according to the vertebral unit level, it was mostly at one level [14 (60.8%)], primarily at the L4-5 vertebral unit [13 (56.5%)]. The sensitivity of detecting LS spondylodiscitis on conventional radiography was found to be 52% (30-65), and the specificity was 86% (59-94). While the median (minimum-maximum) sensitivity was 75.0 (50.0-87.5) in patients with infectious spondylodiscitis, it was 46.6 (13.3-76.9) in patients with spondylodiscitis due to spondyloarthritis. Conclusion: Clinicians can miss spondylodiscitis. Although it is evaluated with conventional radiography in the first stage in the presence of appropriate clinical findings, the clinician should be careful and consider more advanced approaches.

Keywords

• spondyloarthritis
• spondylitis
• inflammation
• sensitivity and specificity