Synchronization of Wave Flows of Arterial and Venous Blood and Phases of the Cardiac Cycle: Part 4

Abstract

Hemodynamic indices of healthy people obtained by catheterization in such vascular areas as the chambers of the heart (both ventricles, both atria, coronary sinus), IVC, SVC, RHV, right renal vein, sigmoid sinus, and aorta were analyzed. Using the mean values of hemodynamic parameters, we constructed graphs of the curves of the central, arterial, and venous pressure, synchronized with each other, with an ECG, and with the peripheral pulse wave. In the present work, to generalize the results obtained, we constructed integral curves of the dynamics of the blood substrate (“bolus,” BB) vector from the entrance (the fusion of venous flows: SVC, IVC, RHV, and coronary sinus) to the exit from the heart-lung-heart system in the form of LVEF. It was revealed that the complete CC consists of two BBs, simultaneously passing the hemodynamic pathway: heart-lung-heart. One BB completes the transformation, leaving PC after contact with the external gaseous medium in the lung and the formation of the pulse wave spheroid in LV, going into SC in the form of LVEF; another BB, after the formation of the pulse wave spheroid in RV, goes into PC, followed by hemodynamic, metabolic and gas transformation. CMIP is a universal indicator of the quality and stability of the relationship of all hemodynamic structures (flows in vessels and heart chambers) included in integral hemodynamic flows (IC-1, IC-2) throughout the complete CC. Changes in the configuration or level of CMIP is an indicator of imbalance and restructuring of the integral indicators of blood flow (therefore, components of hemodynamic flows), indicating a deviation in the parameters of stability of homeostasis as a whole.

Keywords

• cardiac cycle
• hemodynamic parameters
• synchronization
• wave flows