COVID-19 Vaccination Improved Psychological Distress (Anxiety and Depression Scores) in Chronic Kidney Disease Patients: A Prospective Study
Helena Garcia-Llana,
Nayara Panizo,
Lorena Gandía,
Marisa Orti,
Elena Giménez-Civera,
Claudia Forquet,
Luis D’Marco,
Maria Jesús Puchades,
Mari Sargsyan,
Irina Sanchís,
Carmen Ribera,
Mª Inés Marco,
Cristela Moncho Ferrá,
Carmen María Pérez-Baylach,
Begoña Bonilla,
Francesc Moncho Francés,
Elisa Perez-Bernat,
Asunción Sancho,
Jose Luis Górriz
Affiliations
Helena Garcia-Llana
Hospital Universitario La Paz-IdiPAZ, Nephrology Department, Universidad Internacional de La Rioja (UNIR), Centro de Estudios Superiores Cardenal Cisneros, Universidad Pontificia de Comillas de Madrid, 28006 Madrid, Spain
Nayara Panizo
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
Lorena Gandía
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
Marisa Orti
Preventive Medicine Department, Hospital Clínico Universitario de Valencia, 46010 Valencia, Spain
Elena Giménez-Civera
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
Claudia Forquet
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
Luis D’Marco
Universidad Cardenal Herrera-CEU, CEU Universities, 46115 Valencia, Spain
Maria Jesús Puchades
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
Mari Sargsyan
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
Irina Sanchís
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
Carmen Ribera
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
Mª Inés Marco
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
Cristela Moncho Ferrá
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
Carmen María Pérez-Baylach
B-Braun AvitumValnefron Massamagrell Dialysis Centre, 46130 Massamagrell, Spain
Begoña Bonilla
B-Braun AvitumValnefron Valencia Dialysis Centre, 46021 Valencia, Spain
Francesc Moncho Francés
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
Elisa Perez-Bernat
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
Asunción Sancho
Nephrology Department, Hospital Universitario Dr. Peset, 46017 Valencia, Spain
Jose Luis Górriz
Nephrology Department, Hospital Clínico Universitario de Valencia, INCLIVA Health Research Institute, 46010 Valencia, Spain
The purpose of the study is to analyze the impact of vaccination against SARS-CoV-2 on anxiety and depression scores in patients with different modalities of chronic kidney disease. One hundred and seventeen renal patients (50 hemodialysis patients, 13 peritoneal dialysis patients, 32 kidney transplants, and 22 advanced chronic kidney disease patients at pre-dialysis care) were evaluated for depression, anxiety, health-related quality of life (HRQOL), and perceived fears and resources with standardized (Hospital Anxiety and Depression Scale (HADS)) and self-reported questionnaires. The measure points were before vaccination and 15 days after vaccination. The main finding of the study was that there was a decrease in the global mean of normal scores for anxiety and depression symptoms in chronic kidney disease patients post-vaccination. We did not find statistically significant differences in depression or anxiety scores, nor any HRQOL differences between the treatment groups. The three main fears reported by the participants at baseline were those of adverse effects, not getting the vaccine, and lack of information. These findings highlight the potential interest of assessing psychological variables related to the impact of vaccination against SARS-CoV-2. New studies will be required to assess the impact of comprehensive vaccine coverage and its psychological impact.
