Effects of Distal Mutations on Ligand-Binding Affinity in E. coli Dihydrofolate Reductase

• Chen-Hua Huang,
• Yun-Wen Chen,
• Tsun-Tsao Huang,
• Ya-Ting Kao

Affiliations

Chen-Hua Huang

Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan, ROC

Yun-Wen Chen

Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan, ROC

Tsun-Tsao Huang

Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan, ROC

Ya-Ting Kao

Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan, ROC