Communications Biology (Dec 2022)

Single cell multi-omic reference atlases of non-human primate immune tissues reveals CD102 as a biomarker for long-lived plasma cells

Ryan P. Staupe,
Kenneth E. Lodge,
Nithya Thambi,
David Toole,
Alex M. Tamburino,
Dan Chang,
Bonnie J. Howell,
Daria J. Hazuda,
Kalpit A. Vora,
Nicole L. Sullivan

Affiliations

Ryan P. Staupe: Infectious Diseases and Vaccines, MRL, Merck & Co., Inc
Kenneth E. Lodge: LAR, Integrative Vet Medicine, MRL, Merck & Co., Inc.
Nithya Thambi: Infectious Diseases and Vaccines, MRL, Merck & Co., Inc
David Toole: Atlas Data Systems
Alex M. Tamburino: Genome & Biomarker Sciences, MRL, Merck & Co., Inc
Dan Chang: Genome & Biomarker Sciences, MRL, Merck & Co., Inc
Bonnie J. Howell: Infectious Diseases and Vaccines, MRL, Merck & Co., Inc
Daria J. Hazuda: Infectious Diseases and Vaccines, MRL, Merck & Co., Inc
Kalpit A. Vora: Infectious Diseases and Vaccines, MRL, Merck & Co., Inc
Nicole L. Sullivan: Infectious Diseases and Vaccines, MRL, Merck & Co., Inc

DOI: https://doi.org/10.1038/s42003-022-04216-9
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 14

Abstract

CD102 is an enriched biomarker for long-lived plasma cells in non-human primates (NHPs) and is conserved across NHPs, humans, and mice.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

About the journal