Cellular Mechanisms Underlying B Cell Abnormalities in Patients With Gain-of-Function Mutations in the PIK3CD Gene

• Wenjie Wang,
• Qing Min,
• Nannan Lai,
• Krisztian Csomos,
• Ying Wang,
• Luyao Liu,
• Xin Meng,
• Jinqiao Sun,
• Jia Hou,
• Wenjing Ying,
• Qinhua Zhou,
• Bijun Sun,
• Xiaoying Hui,
• Boglarka Ujhazi,
• Sumai Gordon,
• David Buchbinder,
• Catharina Schuetz,
• Manish Butte,
• Jolan E. Walter,
• Jolan E. Walter,
• Xiaochuan Wang,
• Xiaochuan Wang,
• Ji-Yang Wang,
• Ji-Yang Wang,
• Ji-Yang Wang,
• Ji-Yang Wang

Affiliations

Wenjie Wang

Department of Clinical Immunology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, China

Qing Min

Department of Clinical Immunology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, China

Nannan Lai

Key Laboratory of Whole-Period Monitoring and Precise Intervention of Digestive Cancer, Shanghai Municipal Health Commission (SMHC), Minhang Hospital, Fudan University, Shanghai, China

Krisztian Csomos

Division of Pediatric Allergy/Immunology and Jeffrey Modell Diagnostic and Research Center, University of South Florida and Johns Hopkins All Children’s Hospital, St. Petersburg, FL, United States

Ying Wang

Department of Clinical Immunology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, China

Luyao Liu

Department of Clinical Immunology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, China

Xin Meng

Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China

Jinqiao Sun

Department of Clinical Immunology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, China

Jia Hou

Department of Clinical Immunology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, China

Wenjing Ying

Department of Clinical Immunology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, China

Qinhua Zhou

Department of Clinical Immunology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, China

Bijun Sun

Department of Clinical Immunology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, China

Xiaoying Hui

Department of Clinical Immunology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, China

Boglarka Ujhazi

Division of Pediatric Allergy/Immunology and Jeffrey Modell Diagnostic and Research Center, University of South Florida and Johns Hopkins All Children’s Hospital, St. Petersburg, FL, United States

Sumai Gordon

Division of Pediatric Allergy/Immunology and Jeffrey Modell Diagnostic and Research Center, University of South Florida and Johns Hopkins All Children’s Hospital, St. Petersburg, FL, United States

David Buchbinder

Division of Hematology, Children’s Hospital of Orange Country (CHOC), Irvine, CA, United States

Catharina Schuetz

Department of Pediatrics, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

Manish Butte

Division of Immunology, Allergy, and Rheumatology, Department of Pediatrics and Jeffrey Modell Diagnostic and Research Center, University of California, Los Angeles, Los Angeles, CA, United States

Jolan E. Walter

Division of Pediatric Allergy/Immunology and Jeffrey Modell Diagnostic and Research Center, University of South Florida and Johns Hopkins All Children’s Hospital, St. Petersburg, FL, United States

Jolan E. Walter

Massachusetts General Hospital, Boston, MA, United States

Xiaochuan Wang

Department of Clinical Immunology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, China

Xiaochuan Wang

Shanghai Institute of Infectious Disease and Biosecurity, Shanghai, China

Ji-Yang Wang

Department of Clinical Immunology, Children’s Hospital of Fudan University, National Children’s Medical Center, Shanghai, China

Ji-Yang Wang

Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China

Ji-Yang Wang

0Department of Microbiology and Immunology, College of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China

Ji-Yang Wang

1Division of Biochemistry, Faculty of Pharmacy and Graduate School of Pharmaceutical Science, Keio University, Tokyo, Japan